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SPN009

SPN009 (Sequence 3) is a GLP-1 Receptor agonist, with EC50 of 2.84 nM. SPN009 attenuates the type II diabetes in DB/DB mice models[1].

Product Specifications

UNSPSC

12352209

Target

GLP Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/spn009.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](N)CC1=CNC=N1)N[C@](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@@H](C(O)=O)NC(CCCCCCCCCCCCCCCCC(O)=O)=O)=O)=O)=O)=O)C)=O)C)=O)CCC(N)=O)=O)(CC)C)=O)CCC(O)=O)=O)CC(C)C)=O)CC5=CC=C(O)C=C5)=O)CO)=O)CO)=O)C(C)C)=O)CC(O)=O)=O)CO)=O)[C@@H](C)O)=O)CC6=CC=CC=C6)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)(CC)C

Molecular Formula

C191H299N45O59

Molecular Weight

4169.68

References & Citations

[1]Zhao C, et al., Glp-1 agonist polypeptide compound and salt thereof, synthesis method therefor and use thereof. EP4108682.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

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