SPN009
SPN009 (Sequence 3) is a GLP-1 Receptor agonist, with EC50 of 2.84 nM. SPN009 attenuates the type II diabetes in DB/DB mice models[1].
Product Specifications
UNSPSC
12352209
Target
GLP Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/spn009.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)CC1=CNC=N1)N[C@](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@@H](C(O)=O)NC(CCCCCCCCCCCCCCCCC(O)=O)=O)=O)=O)=O)=O)C)=O)C)=O)CCC(N)=O)=O)(CC)C)=O)CCC(O)=O)=O)CC(C)C)=O)CC5=CC=C(O)C=C5)=O)CO)=O)CO)=O)C(C)C)=O)CC(O)=O)=O)CO)=O)[C@@H](C)O)=O)CC6=CC=CC=C6)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)(CC)C
Molecular Formula
C191H299N45O59
Molecular Weight
4169.68
References & Citations
[1]Zhao C, et al., Glp-1 agonist polypeptide compound and salt thereof, synthesis method therefor and use thereof. EP4108682.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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