Salsolidine (hydrochloride)

Salsolidine hydrochloride, a tetrahydroisoquinoline alkaloid, acts as a stereoselective competitive MAO A (monoamine oxidase A) inhibitor.

Product Specifications

CAS Number

[63283-42-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Monoamine Oxidase

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/salsolidine-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

CC1NCCC2=C1C=C(OC)C(OC)=C2.Cl

Molecular Formula

C12H18ClNO2

Molecular Weight

243.73

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Bembenek ME, et al. Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines. J Med Chem. 1990 Jan;33 (1) :147-52.|[2]Airaksinen MM, et al. Binding of beta-carbolines and tetrahydroisoquinolines by opiate receptors of the delta-type. Acta Pharmacol Toxicol (Copenh) . 1984 Nov;55 (5) :380-5.|[3]Tundis R, et al. A potential role of alkaloid extracts from Salsola species (Chenopodiaceae) in the treatment of Alzheimer's disease. J Enzyme Inhib Med Chem. 2009 Jun;24 (3) :818-24.