Helveticoside

Helveticoside (Strophanthidin-digitoxoside) is a helveticosid, possesses an ED50 of 0.17 μM for isolated guinea-pig ileum. Helveticoside has anticancer effect[1][2].

Product Specifications

CAS Number

[630-64-8]

Product Name Alternative

Strophanthidin-digitoxoside

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/helveticoside.html

Purity

95.20

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C[C@@]12[C@]3([H])[C@](CC[C@@]1(C[C@H](CC2)O[C@H]4C[C@@H]([C@@H]([C@H](O4)C)O)O)O)([H])[C@@]5([C@](CC3)([C@@H](C(CO6)=CC6=O)CC5)C)O

Molecular Formula

C29H42O9

Molecular Weight

534.64

References & Citations

[1]K O Haustein, et al. Structure-activity relationship of natural and semi-synthetic genins and glycosides as investigated on the smooth muscle of the guinea-pig ileum. Pharmacology. 1973;10 (2) :65-75.|[2]An N, et al. Helveticoside Exhibited p53-dependent Anticancer Activity Against Colorectal Cancer. Arch Med Res. 2020 Apr;51 (3) :224-232.