Enbezotinib
Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer[1].
Product Specifications
CAS Number
2359649-81-1
Product Name Alternative
TPX-0046
UNSPSC
12352005
Target
RET
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/enbezotinib.html
Purity
99.50
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
FC(C=C1CN2C3=NC4=C5C=NN4C=C3O[C@]6([H])[C@@]2([H])CCC6)=CN=C1O[C@@H](C)CNC5=O
Molecular Formula
C21H21FN6O3
Molecular Weight
424.43
References & Citations
[1]ROGERS EW, et, al. Macrocyclic compounds for treating disease. WO2019126121A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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