Enbezotinib

2359649-81-1

TPX-0046

12352005

RET

Reference compound

Protein Tyrosine Kinase/RTK

Cancer-Kinase/protease

Cancer

https://www.medchemexpress.com/enbezotinib.html

99.50

DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)

FC(C=C1CN2C3=NC4=C5C=NN4C=C3O[C@]6([H])[C@@]2([H])CCC6)=CN=C1O[C@@H](C)CNC5=O

C21H21FN6O3

424.43

[1]ROGERS EW, et, al. Macrocyclic compounds for treating disease. WO2019126121A1.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

Reference compound1

Phase 2