1,3-Dibromo-5,5-dimethylhydantoin

1,3-Dibromo-5,5-dimethylhydantoin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[77-48-5]

UNSPSC

12352005

Hazard Statement

H272, H301, H314, H317, H400

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1-3-dibromo-5-5-dimethylhydantoin.html

Purity

99.03

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1N(Br)C(C(C)(C)N1Br)=O

Molecular Formula

C5H6Br2N2O2

Molecular Weight

285.92

Precautions

H272, H301, H314, H317, H400

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl-Chain Linkers

Available Sizes

Curated Selection

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