Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (5F8E1) (XBB.1.5/Omicron Specific)

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.

Immobilized SARS-CoV-2 Spike Trimer Protein, His Tag (XBB/Omicron) (MALS verified) (Cat. No. SPN-C5248), SARS-CoV-2 Spike Trimer Protein, His Tag (XBB.1/Omicron) (MALS verified) (Cat. No. SPN-C522t) and SARS-CoV-2 Spike Trimer Protein, His Tag (XBB.1.5/Omicron) (MALS verified) (Cat. No. SPN-C524i) can bind Anti-SARS-CoV-2 Spike RBD Antibody, Mouse IgG1 (5F8E1) (XBB.1.5/Omicron Specific) (Cat. No. SPD-Y171) with a linear range of 0.098-6.25 ng/mL (QC tested). The antibody does not bind Spike Protein of WT (Cat. No. SPN-C52H9), Alpha (Cat. No. SPN-C52H6), Beta, Gamma (Cat. No. SPN-C52Hg), Delta (Cat. No. SPN-C52He), B.1.1.529/Omicron (Cat. No. SPN-C52Hz), BA.2/Omicron (Cat. No. SPN-C5223), BA.3/Omicron (Cat. No. SPN-C5225), BA.4/Omicron (Cat. No. SPN-C5229), BA.5/Omicron (Cat. No. SPN-C522e), BA.2.12.1/Omicron (Cat. No. SPN-C522d), BQ.1.1/Omicron (Cat. No. SPN-C522s), BA.2.75/Omicron (Cat. No. SPN-C522f), BA.4.6/Omicron (Cat. No. SPN-C522m), BF.7/Omicron (Cat. No. SPN-C522q) (QC tested).