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PE-Labeled Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (Site-specific conjugation)

PE-Labeled Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM122) is a PE-labeled chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain.

Product Specifications

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Host

HEK293

Origin Species

Mouse

Target

Spike RBD

Conjugation

PE Labeled

Tag

Human IgG1 | Human Kappa

Applications

Flow Cytometry (Neutralizing assay) .

Stability

● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please protect from light and avoid repeated freeze-thaw cycles.

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose and BSA

Shipping Conditions

RT

Storage Conditions

-20°C, aviod light

Package Size

25tests*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/SPD-PM226.pdf

Species

Mouse

CAS Number

9007-83-4

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