PE-Labeled Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (Site-specific conjugation)
PE-Labeled Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM122) is a PE-labeled chimeric monoclonal antibody recombinantly expressed from HEK293 cells, which combines the variable region of a mouse monoclonal antibody with human IgG1 constant domain.
Product Specifications
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Host
HEK293
Origin Species
Mouse
Target
Spike RBD
Conjugation
PE Labeled
Tag
Human IgG1 | Human Kappa
Applications
Flow Cytometry (Neutralizing assay) .
Stability
● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please protect from light and avoid repeated freeze-thaw cycles.
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose and BSA
Shipping Conditions
RT
Storage Conditions
-20°C, aviod light
Package Size
25tests*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/SPD-PM226.pdf
Species
Mouse
CAS Number
9007-83-4
Curated Selection
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