Anti-SARS-CoV-2 Spike S2 Antibody, Human IgG4 (AS86)

Anti-SARS-CoV-2 Spike S2 Antibody, Human IgG4 (AS86) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from CHO cells.

Product Specifications

Background

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

CAS Number

9007-83-4

Host

CHO

Origin Species

Human

Target

Spike S2

Conjugation

Unconjugated

Tag

Human IgG4 | Human Kappa

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.

Purity

0.95

Bioactivity

Immobilized SARS-CoV-2 S2 protein, His Tag (Cat. No. S2N-C52H5) at 2 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Spike S2 Antibody, Human IgG4 (AS86) (Cat. No. S2N-S86) with a linear range of 0.24-3.91 ng/mL (QC tested).