Anti-SARS-CoV-2 Spike S1 Antibody, Mouse IgG1 (AS59)

Anti-SARS-CoV-2 Spike S1 Antibody, Mouse IgG1 (AS59) (S1N-S59A1), originally from mouse immunized with recombinant SARS-CoV-2 Spike S1 protein, is produced from hybridoma.

Product Specifications

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

CAS Number

9007-83-4

Host

Hybridoma

Origin Species

Mouse

Target

Spike S1

Conjugation

Unconjugated

Tag

Mouse IgG1 | Mouse Kappa

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.

Purity

0.95

Bioactivity

Immobilized SARS-CoV-2 S protein RBD, His Tag (Cat. No. SPD-C52H1) at 2 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Spike S1 Antibody, Mouse IgG1 (AS59) (Cat. No. S1N-S59A1) with a linear range of 0.08-3 ng/mL (QC tested).