(7S)-BAY-593
Product Specifications
UNSPSC Description
(7S)-BAY-593 is the S-enantiomer of BAY-593 (HY-161573). BAY-593 is an orally active GGTase-I inhibitor. BAY-593 can block YAP1/TAZ signaling in animals and has antitumor activity[1].
Target Antigen
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/7s-bay-593.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N1CCC2(CCNC[C@]2([H])C3=CC=CC=C3OC)CC1)[C@@](OC)(C(F)(F)F)C4=CC=CC=C4
Molecular Weight
476.53
References & Citations
[1]Graham K, et al. Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling. Cell Chem Biol. 2024 Mar 19:S2451-9456(24)00087-4.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-161573A/7S-BAY-593-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-161573A/7S-BAY-593-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2413068-25-2
Available Sizes
Curated Selection
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