Biotinylated Human KREMEN2 Protein, His, Avitag™
Kremen2 (Krm2) plays an important role in embryonic development, bone formation, and tumorigenesis as a crucial regulator of classical Wnt/β-catenin signaling pathway. Krm1 and its paralog Krm2 share the ability to bind Dkk1 and inhibit Wnt signaling, both processes previously shown to rely on the extracellular domain. Previous studies have shown that Krm2 may be involved in embryonic development, bone formation, neural ridge formation and tumorigenesis and could be a biomarker of grading and a potential therapeutic target in gastric cancer.
Product Specifications
Background
Specifications
Accession Number
Q8NCW0-1
Expression Region
Cys 219 - Leu 326
Host
HEK293
Target
KREMEN2
Conjugation
Biotin-labeled
Tag
C-10xHis & C-Avi
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
0.2 M Arginine, PBS, pH7.4
Additives
Trehalose
Molecular Weight
18.5 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
25ug*1
Host or Source
HEK293
Species
Human
Protein ID
Q8NCW0-1
Preservative
Trehalose
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