CK2-IN-14
CK2-IN-14 (Compound 10b) is an inhibitor for cyclin kinase 2α with an IC50 of 36.7 nM. CK2-IN-14 inhibits the growth of cancer cell 786-O and U937 with GI50 of 7.3 μM and 7.5 μM[1].
Product Specifications
UNSPSC
12352101
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ck2-in-14.html
Smiles
ClC1=CC=C(C=C1)N2CCN(CC2)C3=NC=NC4=C3C5=C(S4)CNCC5
Molecular Formula
C19H20ClN5S
Molecular Weight
385.91
References & Citations
[1]Khalifa H, et al., Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold. Eur J Med Chem. 2025 Jan 15;282:117048.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK2
Frequently Asked Questions
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