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CK2-IN-14

CK2-IN-14 (Compound 10b) is an inhibitor for cyclin kinase 2α with an IC50 of 36.7 nM. CK2-IN-14 inhibits the growth of cancer cell 786-O and U937 with GI50 of 7.3 μM and 7.5 μM[1].

Product Specifications

UNSPSC

12352101

Target

Casein Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ck2-in-14.html

Smiles

ClC1=CC=C(C=C1)N2CCN(CC2)C3=NC=NC4=C3C5=C(S4)CNCC5

Molecular Formula

C19H20ClN5S

Molecular Weight

385.91

References & Citations

[1]Khalifa H, et al., Discovery of a novel, selective CK2 inhibitor class with an unusual basic scaffold. Eur J Med Chem. 2025 Jan 15;282:117048.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CK2

Frequently Asked Questions

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