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Human PADI3 Protein, His Tag

Human PADI3 Protein, His Tag (PA3-H5544) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Pro 664 (Accession # Q9ULW8) .

Product Specifications

Background

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]

Specifications

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 76.8 kDa. The protein migrates as 75-85 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q9ULW8

Expression Region

Met 1 - Pro 664

Host

Insect Cells

Target

PADI3

Conjugation

Unconjugated

Tag

N-10xHis

Source

Human

Stability

● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Liquid

Buffer

50mM Tris, 150mM NaCl, pH7.5

Additives

Glycerol

Molecular Weight

76.8 kDa

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

50ug*1

Species

Human

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