Mouse EGF R Protein, Fc Tag (MALS verified)
Mouse EGF R Protein, Fc Tag (EGR-M5257) is expressed from human 293 cells (HEK293) . It contains AA Leu 25 - Ser 647 (Accession # Q01279-1) .
Product Specifications
Background
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4) . Mutations affecting EGFR expression or activity could result in cancer.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 95.7 kDa. The protein migrates as 110-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q01279-1
Expression Region
Leu 25 - Ser 647
Host
HEK293
Target
EGF R
Conjugation
Unconjugated
Tag
C-Fc
Source
Mouse
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Mouse EGF R Protein, Fc Tag (Cat. No. EGR-M5257) at 5 μg/mL (100 μL/well) can bind Human EGF, Mouse IgG2a Fc Tag (Cat. No. EGF-H525b) with a linear range of 0.5-63 ng/mL (QC tested).
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
95.7 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/EGR-M5257.pdf
Species
Mouse
Curated Selection
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