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Cynomolgus CD24 Protein, His Tag

Cynomolgus CD24 Protein, His Tag (CD4-C52H5) is expressed from human 293 cells (HEK293) . It contains AA Thr 27 - Lys 54 (Accession # I7GKK1-1) .

Product Specifications

Background

CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 4.9 kDa. The protein migrates as 25-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

I7GKK1-1

Expression Region

Thr 27 - Lys 54

Host

HEK293

Target

CD24

Conjugation

Unconjugated

Tag

C-10xHis

Source

Cynomolgus

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

4.9 kDa

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

500ug*2

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/CD4-C52H5.pdf

Species

Cynomolgus

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