Cynomolgus Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free
Selected Variant
IT3-C52W3-1mg
Size: 1 mg
Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Product Specifications
Background
Specifications
Accession Number
A0A2K5WCD3-1 & A0A2K5WYN9
Expression Region
Phe 31 - Pro 993 & Gly 27 - Asp 718
Host
HEK293
Target
Integrin alpha V beta 3
Conjugation
Unconjugated
Tag
C-10xHis | Native
Source
Cynomolgus
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
50 mM Tris, 150 mM NaCl, pH8.0
Additives
Trehalose
Molecular Weight
113 kDa & 81.7kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Host or Source
HEK293
Species
Cynomolgus
Protein ID
A0A2K5WCD3-1 & A0A2K5WYN9
Preservative
Trehalose
Price
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