Human CD5 Protein, Fc Tag (MALS verified)
Human CD5 Protein, Fc Tag (CD5-H5255) is expressed from human 293 cells (HEK293) . It contains AA Leu 159 - Pro 372 (Accession # P06127-1) .
Product Specifications
Background
CD5 protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes, and a subset of B lymphocytes. It serves to mitigate activating signals from the BCR, allowing B-1 cells to be activated only by strong stimuli. Additionally, CD5 is involved in regulating lipid synthesis and inflammatory responses.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.1 kDa. The protein migrates as 55-57 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P06127-1
Expression Region
Leu 159 - Pro 372
Host
HEK293
Target
CD5
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Human CD5 Protein, Fc Tag (Cat. No. CD5-H5255) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CD5 Antibody, Mouse IgG1 (2C8A7) with a linear range of 0.06-4 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
50.1 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CD5-H5255.pdf
Species
Human
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