Human TNFR2 / CD120b / TNFRSF1B Protein, Fc Tag (MALS verified)
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
Product Specifications
Background
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.6 kDa. The protein migrates as 66-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P20333-1
Expression Region
Leu 23 - Asp 257
Host
HEK293
Target
TNFR2
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Human TNFR2 / CD120b / TNFRSF1B Protein, Fc Tag (Cat. No. TN2-H5253) at 5 μg/mL (100 μL/well) can bind Biotinylated Human TNF-alpha, His,Avitag (Cat. No. TNA-H82E3) with a linear range of 0.1-6 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
51.6 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
50ug*1
Host or Source
HEK293
Species
Human
Protein ID
P20333-1
Preservative
Trehalose
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15169475 1 Vial
Lentiviral mouse Polg shRNA (UAS) - Lentiviral mouse Polg shRNA (UAS, RFP) (25)
Ask
View Details 
MBS6307431-01 0.2 mL
HNF4A, NT (HNF4A, HNF4, NR2A1, TCF14, Hepatocyte nuclear factor 4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, Transcription factor HNF-4) (Biotin)
Ask
View Details MBS6307431-02 5x 0.2 mL
HNF4A, NT (HNF4A, HNF4, NR2A1, TCF14, Hepatocyte nuclear factor 4-alpha, Nuclear receptor subfamily 2 group A member 1, Transcription factor 14, Transcription factor HNF-4) (Biotin)
Ask
View Details MBS6258186-01 0.1 mL
Ezrin (Radixin, Moesin, Cytovillin, p81, Membrane-organizing extension spike protein) (APC)
Ask
View Details