Human LYPD1 / PHTS Protein, His Tag
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha-4:beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety.
Product Specifications
Background
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha-4:beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.4 kDa. The protein migrates as 18-20 kDa and 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q8N2G4-1
Expression Region
Leu 21 - Gly 115
Host
HEK293
Target
LYPD1
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Human LYPD1 Protein, His Tag (Cat. No. LY1-H52H3) at 1 μg/mL (100 μL/well) can bind Anti-LYPD1 antibody with a linear range of 0.02-0.313 μg/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
12.4 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Human
Protein ID
Q8N2G4-1
Preservative
Trehalose
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