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Human Tau-441 (K18, P301L) Protein, Tag Free, low endotoxin (MALS verified)

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Product Specifications

Background

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Specifications

This protein carries no "tag". The protein has a calculated MW of 13.8 kDa. The protein migrates as 14-15 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .

Accession Number

P10636-8 (P301L)

Expression Region

Gln 244 - Glu 372

Host

E. coli

Target

Tau

Conjugation

Unconjugated

Tag

Native

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

0.01 EU per μg

Purity

95%

Format

Liquid

Buffer

20 mM Tris, 150 mM NaCl, pH7.5

Additives

Trehalose

Molecular Weight

13.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

1mg*1

Host or Source

E. coli

Species

Human

Protein ID

P10636-8 (P301L)

Preservative

Trehalose

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