Biotinylated Mouse Siglec-2 / CD22 Protein, His Tag, ultra sensitivity (primary amine labeling) (MALS verified)
B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Product Specifications
Background
Specifications
Accession Number
P35329-1
Expression Region
Asn 21 - Glu 1395 (LTBP-1s) | Leu 30 - Ser 390 (TGF-beta 1)
Host
HEK293
Target
Siglec-2
Conjugation
Biotin-labeled
Tag
C-10xHis
Source
Mouse
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
78.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
25ug*1
Host or Source
HEK293
Species
Mouse
Protein ID
P35329-1
Preservative
Trehalose
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