Human AMIGO2 Protein, His Tag

Human AMIGO2, His Tag (AM2-H52H5) is expressed from human 293 cells (HEK293). It contains AA Val 31 - Thr 398 (Accession # Q86SJ2-1).

Product Specifications

Background

Gastric cancer (GC) is one of the most common malignancies, and the liver is the most common site of hematogenous metastasis of GC. AMIGO2 is a type I transmembrane protein that has been implicated in tumour cell adhesion in adenocarcinomas; however, its importance in GC remains undetermined.But more data highlight AMIGO2 as a new target for a novel anti-metastatic therapeutic approach aimed at blocking cohesion, survival, and adhesion of metastatic tumorspheres.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 43.5 kDa. The protein migrates as 58-62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

Val 31 - Thr 398

Host

HEK 293

Target

AMIGO2

Conjugation

Unconjugated

Tag

C-10×His

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.