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Human CD133 Full Length Protein (VLP)

Human CD133 Full Length-VLP (CD3-H52P3) is expressed from human 293 cells (HEK293) . It contains AA Gly 20 - His 865 (Accession # O43490-1) .

Product Specifications

Background

Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

Specifications

This protein .

Accession Number

O43490-1

Expression Region

Gly 20 - His 865

Host

HEK293

Target

CD133

Conjugation

Unconjugated

Source

Human

Stability

● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 12 months under sterile conditions.

Endotoxin

1.0 EU per μg

Bioactivity

Immobilized Human CD133 Full Length-VLP (Cat. No. CD3-H52P3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CD133 Antibody,Mouse IgG1 with a linear range of 0.2-4 ng/mL (QC tested).

Format

Liquid

Buffer

PBS, pH7.4

Additives

Trehalose

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

500ug*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/CD3-H52P3.pdf

Species

Human

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