PE-Labeled Human LTBR / TNFRSF3 Protein, His Tag (Site-specific conjugation)

PE-Labeled Human LTBR, His Tag (Cat. No.LTR-HP2H3) is produced via site-specific conjugation of PE to Human LTBR, His Tag under optimal conditions with a proprietary technology. Human LTBR, His Tag is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Met 227 (Accession # P36941-1).

Product Specifications

Background

Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.3 kDa.

Expression Region

Gln 31 - Met 227

Host

HEK 293

Target

LTBR

Conjugation

PE Labeled

Tag

C-10×His

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.