Human Neurogranin Protein, His Tag
Human Neurogranin, His Tag (NEN-H5144) is expressed from E. coli cells. It contains AA Met 1 - Asp 78 (Accession # Q92686) .
Product Specifications
Background
Neurogranin is as a small protein encoded by the NRGN gene. it is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin is the main postsynaptic protein regulating the availability of calmodulin, binding to it in the absence of calcium. Phosphorylation by protein kinase C lowers its binding ability. It is a potential biomarker of neurological and mental diseases.
Specifications
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 9.5 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE) .
Accession Number
Q92686
Expression Region
Met 1 - Asp 78
Host
E. coli
Target
Neurogranin
Conjugation
Unconjugated
Tag
N-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
20 mM Tris, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
9.5 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/NEN-H5144.pdf
Species
Human
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