Human SMN1 Protein, His Tag
SMN1 is produced chiefly by the SMN1 gene, located on the telomeric portion of chromosome 5q. SMN1 protein is one of a group of proteins called the SMN complex, which is important for the maintenance of specialized nerve cells called motor neurons. In cells, the SMN complex plays an important role in processing mRNA. The SMN complex helps to assemble the cellular machinery needed to process pre-mRNA. The SMN complex is also important for the development of specialized outgrowths from nerve cells called dendrites and axons. Deletion or mutation of the SMN1 gene results in a reduced level of full-length SMN protein and manifests as a range of neuromuscular phenotypes in humans as the disease spinal muscular atrophy (SMA) .
Product Specifications
Background
Specifications
Accession Number
Q16637-1
Expression Region
Ala 2 - Asn 294
Host
E. coli
Target
SMN1
Conjugation
Unconjugated
Tag
N-10xHis
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Format
Powder
Buffer
PBS, 0.5 M Arginine, pH7.4
Additives
Trehalose
Molecular Weight
33.7 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
E. coli
Species
Human
Protein ID
Q16637-1
Preservative
Trehalose
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