Human Growth Hormone (GH) Protein, premium grade

Growth hormone (GH or GH-N) is also known as Somatotropin, Pituitary growth hormone. GH belongs to the somatotropin/prolactin family. Growth hormone (GH) may form monomer, dimer, trimer, tetramer and pentamer, by disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. GH can also form a complex either with GHBP or with the alpha2-macroglobulin complex. Growth hormone (GH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

Product Specifications

Background

Specifications

This protein carries no "tag". The protein has a calculated MW of 22.3 kDa. The protein migrates as 21-22 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .

Accession Number

P01241-1

Expression Region

Phe 27 - Phe 217

Host

E. coli

Target

Growth Hormone

Conjugation

Unconjugated

Tag

Native

Source

Human

Stability

-70°C for 24 months under sterile conditions.

Endotoxin

0.1 EU per μg

Purity

95%

Bioactivity

Immobilized Human GH, premium grade (Cat. No. GH1-H4118) at 2 μg/mL (100 μL/well) can bind Human GHR, His Tag (Cat. No. GHR-H5222) with a linear range of 0.1-2 ng/mL (QC tested).