Cynomolgus CLEC12A / MICL / CLL-1 Protein, His Tag
Cynomolgus CLEC12A, His Tag (CLA-C5246) is expressed from human 293 cells (HEK293) . It contains AA His 32 - Ala 232 (Accession # A0A2K5WXQ6-1) .
Product Specifications
Background
CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
Specifications
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 25.5 kDa. The protein migrates as 34-46 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
A0A2K5WXQ6-1
Expression Region
His 32 - Ala 232
Host
HEK293
Target
CLEC12A
Conjugation
Unconjugated
Tag
N-10xHis
Source
Cynomolgus
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
25.5 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CLA-C5246.pdf
Species
Cynomolgus
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