Human CCL24/Eotaxin-2 Protein, His Tag (HPLC verified)
Human CCL24, His Tag (CC4-H52H1) is expressed from human 293 cells (HEK293) . It contains AA Val 27 - Cys 119 (Accession # O00175) .
Product Specifications
Background
C-C motif chemokine ligand 24 (CCL24), also known as eotaxin2, belongs to CC chemokines like MCP-1, and it mainly chemoattracts eosinophils. CCL24 can promote the separation of eosinophils from endothelial cells and then combine with its sole ligand to promote eosinophils to enter the tissue. CCL24 was not originally found in eosinophils but was first isolated from monocytes. Latest, it was found that the expression of CCL24 in the bronchial epithelial cells of asthma patients increased. CCL24 promotes immune cell trafficking and activation as well as profibrotic activities through the CCR3 receptor (C-C chemokine receptor type 3) . Both CCL24 and CCR3 is involved in lung and skin inflammation and fibrosis.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.3 kDa. The protein migrates as 18-21 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
O00175
Expression Region
Val 27 - Cys 119
Host
HEK293
Target
CCL24
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
12.3 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CC4-H52H1.pdf
Species
Human
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
