Alexa Fluor™ 488-Labeled Human BCMA / TNFRSF17 Protein, His TagStar Staining

Alexa Fluor 488-Labeled Human BCMA, His Tag (BCA-HA2H8) is produced via conjugation of AF488 to Human BCMA, His Tag with a new generation site-specific technology under Star Staining labeling platform. Human BCMA, His Tag is expressed from human 293 cells (HEK293) . It contains AA Met 1 - Ala 54 (Accession # Q02223-1) .

Product Specifications

Background

Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.

Specifications

This protein carries a polyhistidine tag at the C-terminus.

Accession Number

Q02223-1

Expression Region

Met 1 - Ala 54

Host

HEK293

Target

BCMA

Conjugation

AF488 Labeled

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.