Canine FcRn / FCGRT&B2M Heterodimer Protein, His Tag&Tag Free (MALS & SPR verified)
Selected Variant
FCM-C52W8-100ug
Size: 100 µg
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Product Specifications
Background
Specifications
Accession Number
XP_038512242.1 (FCGRT) & NP_001271408.1 (B2M)
Expression Region
Ala 23 - Pro 298 (FCGRT) & Val 28 - Asn 125 (B2M)
Host
HEK293
Target
FcRn (FCGRT & B2M)
Conjugation
Unconjugated
Tag
C-10xHis | Native
Source
Canine
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
32.3 kDa (FCGRT) & 11.6 kDa (B2M)
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Canine
Protein ID
XP_038512242.1 (FCGRT) & NP_001271408.1 (B2M)
Preservative
Trehalose
Price
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