Human IgE Fc Protein, His Tag (MALS verified)
Human IgE Fc, His Tag (IGE-H52H9) is expressed from human 293 cells (HEK293) . It contains AA Ser 106 - Gly 427 (Accession # P01854-1) .
Product Specifications
Background
As one of the five designated immunoglobulin isotypes, immunoglobulin E (IgE) plays a major role in atopic conditions by inducing immediate hypersensitivity reactions. IgE also contributes significantly to the body’s immune response to parasitic infections. IgE antibodies are predominantly found in the tissues, firmly attached to effector cells, such as mast cells and basophils, by high-affinity IgE Fc receptor (Fc epsilon RI) and low-affinity IgE receptor (Fc epsilon RII) .
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.6 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P01854-1
Expression Region
Ser 106 - Gly 427
Host
HEK293
Target
IgE Fc
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Human Fc epsilon RI alpha, Fc Tag (Cat. No. FCA-H5259) at 5 μg/mL (100 μL/well) can bind Human IgE Fc, His Tag (Cat. No. IGE-H52H9) with a linear range of 0.6-10 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
37.6 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/IGE-H52H9.pdf
Species
Human
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