Mouse IL-1RL1 / ST2 Protein, Fc Tag
Mouse IL-1RL1, Fc Tag (IL1-M5259) is expressed from human 293 cells (HEK293) . It contains AA Ser 27 - Arg 332 (Accession # P14719-1) .
Product Specifications
Background
Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 61.5 kDa. The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P14719-1
Expression Region
Ser 27 - Arg 332
Host
HEK293
Target
IL-1RL1
Conjugation
Unconjugated
Tag
C-Fc
Source
Mouse
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
61.5 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
200ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/IL1-M5259.pdf
Species
Mouse
Curated Selection
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