What is the catalog number for Mouse IL-17C Protein, His Tag?

The catalog number for Mouse IL-17C Protein, His Tag is ILC-M52H7-100ug.

What sizes are available for Mouse IL-17C Protein, His Tag?

Mouse IL-17C Protein, His Tag is available in the following size(s): 100 µg.

Is Mouse IL-17C Protein, His Tag in stock?

Mouse IL-17C Protein, His Tag is currently made to order / not held in immediate stock. Contact us for lead time.

What are the weight and dimensions of Mouse IL-17C Protein, His Tag?

Mouse IL-17C Protein, His Tag has the following package details: 100ug*1.

Who manufactures Mouse IL-17C Protein, His Tag?

Mouse IL-17C Protein, His Tag is manufactured by CRB.

What is the estimated delivery time for Mouse IL-17C Protein, His Tag?

Estimated delivery time for Mouse IL-17C Protein, His Tag is approximately 10 business day(s), depending on your location.

Mouse IL-17C Protein, His Tag

Interleukin-17C (IL-17C) is a glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. IL‑17C binds to IL‑17 RE with high affinity and to IL‑17 RA with low affinity, binds to a heterodimer formed by IL17RA and IL17RE. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.7 kDa. The protein migrates as 25-27 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q8K4C5-1

Expression Region

Asp 17 - Gln 194

Host

HEK293

Target

IL-17C

Conjugation

Unconjugated

Tag

C-10xHis

Source

Mouse

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Human IL-17 RE (155-454), Fc Tag (Cat. No. ILE-H5256) at 5 μg/mL (100 μL/well) can bind Mouse IL-17C, His Tag (Cat. No. ILC-M52H7) with a linear range of 0.2-16 ng/mL (QC tested).