Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human CD45RA / PTPRC protein, His Tag

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

Product Specifications

Background

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53.2 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P08575-8

Expression Region

Gln 26 - Lys 482

Host

HEK293

Target

CD45RA

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

53.2 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

P08575-8

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SSX7 HDR Plasmid (h)
sc-403553-HDR 20 µg

SSX7 HDR Plasmid (h)

Ask
View Details
Amfonelic Acid
527833 5.0mg

Amfonelic Acid

Ask
View Details
Mouse Monoclonal ZBTB37 Antibody (OTI1D7) [CoraFluor 1]
NBP2-74907CL1 0.1 mL

Mouse Monoclonal ZBTB37 Antibody (OTI1D7) [CoraFluor 1]

Ask
View Details
Recombinant Cucumis sativus Acidic endochitinase
MBS1073523-01 0.02 mg (E-Coli)

Recombinant Cucumis sativus Acidic endochitinase

Ask
View Details
Recombinant Cucumis sativus Acidic endochitinase
MBS1073523-02 0.02 mg (Yeast)

Recombinant Cucumis sativus Acidic endochitinase

Ask
View Details
Recombinant Cucumis sativus Acidic endochitinase
MBS1073523-03 0.1 mg (E-Coli)

Recombinant Cucumis sativus Acidic endochitinase

Ask
View Details