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Human Cathepsin S / CTSS Protein, His Tag (active enzyme, MALS verified)

Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family. Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.

Product Specifications

Background

Cathepsin S is also known as CTSS, which is a member of the peptidase C1 family. Cathepsin S is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages. The catalytic activity of cathepsin S is similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.7 kDa & 25.9 kDa. The protein migrates as 38-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P25774-1

Expression Region

Gln 17 - Ile 331 & Leu 115 - Ile 331

Host

HEK293

Target

Cathepsin S

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Liquid

Buffer

12.5 mM MES, 75 mM NaCl, pH6.5

Additives

Glycerol

Molecular Weight

37.7 kDa & 25.9 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

1mg*1

Host or Source

HEK293

Species

Human

Protein ID

P25774-1

Preservative

Glycerol

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