Human Siglec-7 / CD328 Protein, Fc (L117A, L118A) Tag, low Endotoxin (MALS verified)
Siglec-7 is a member of the human CD33‐related Siglec receptor. The extracellular region of Siglec‐7 is characterized by an N‐terminal V‐set Ig domain that can bind sialic acid and two C2‐set Ig domains. The cytoplasmic tail of Siglec‐7 has one immune‐receptor tyrosine‐based inhibitory motif (ITIM) and one ITIM‐like motif. Siglec-7 is considered as a sialic acid-dependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells.
Product Specifications
Background
Specifications
Accession Number
Q9Y286-1 (L117A, L118A)
Expression Region
Gln 19 - Leu 353
Host
HEK293
Target
Siglec-7
Conjugation
Unconjugated
Tag
C-Fc (A2)
Source
Human
Stability
Endotoxin
0.01 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
25 mM MES, 150 mM NaCl, pH5.5
Additives
Trehalose
Molecular Weight
63.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
50ug*1
Host or Source
HEK293
Species
Human
Protein ID
Q9Y286-1
Preservative
Trehalose
Frequently Asked Questions
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