Human Endoglin / CD105 Protein, His Tag
Endoglin (ENG), endothelial glycoprotein, also known as CD105, is a coreceptor of the transforming growth factor-β (TGFβ) family signaling complex, which is highly expressed on endothelial cells and plays a key role in angiogenesis. It regulates the responses associated with binding to transforming growth factor β1 egg (Activin-A), bone morphogenetic protein 2 (BMP-2), and bone morphogenetic protein 7 (BMP-7) . Endoglin may be involved in autosomal dominant disease, such as hereditary hemorrhagic telangiectasia 1 (HHT1) . Circulating soluble ENG is also elevated in pulmonary arterial hypertension (PAH) and is proposed to be a biomarker for the prognosis of group I PAH patients.
Product Specifications
Background
Specifications
Accession Number
P17813-1
Expression Region
Glu 26 - Gly 586
Host
HEK293
Target
Endoglin
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
62.6 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
50ug*1
Host or Source
HEK293
Species
Human
Protein ID
P17813-1
Preservative
Trehalose
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