Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human IL-21 R & IL-2 R gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

Selected Variant

ILA-H52W9-100ug

Size: 100 µg

Interleukin (IL) -21, IL-2, IL-4, IL-7, IL-9, and IL-15 form a family of cytokines based on their sharing the common cytokine receptor γ chain (γc), which was originally discovered as the third receptor component of the IL-2 receptor, IL-2RG. IL-21 is a class I cytokine that exerts pleiotropic effects on both innate and adaptive immune responses. It signals through a heterodimeric receptor complex consisting of the IL-21 receptor (IL-21R) and the common γ-chain.

Product Specifications

Background

Interleukin (IL) -21, IL-2, IL-4, IL-7, IL-9, and IL-15 form a family of cytokines based on their sharing the common cytokine receptor γ chain (γc), which was originally discovered as the third receptor component of the IL-2 receptor, IL-2RG. IL-21 is a class I cytokine that exerts pleiotropic effects on both innate and adaptive immune responses. It signals through a heterodimeric receptor complex consisting of the IL-21 receptor (IL-21R) and the common γ-chain.

Specifications

Human IL-21 R & IL-2 R gamma Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of IL-21 R and IL-2 R gamma, has a calculated MW of 51.5 kDa (IL-21 R) & 53.6 kDa (IL-2 R gamma) . Subunit IL-21 R is fused with a human IgG1 Fc tag at the C-terminus and subunit IL-2 R gamma is fused with a human IgG1 Fc tag at the C-terminus. The protein migrates as 65 kDa and 70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q9HBE5-1 (IL-21 R) & P31785-1 (IL-2 R gamma)

Expression Region

Cys 20 - Pro 236 (IL-21 R) & Leu 23 - Asn 254 (IL-2 R gamma)

Host

HEK293

Target

IL-21 R & IL-2 R gamma

Conjugation

Unconjugated

Tag

C-Fc | C-Fc

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Human IL-21, Tag Free (Cat. No. IL1-H5213) at 5 μg/mL (100 μL/well) can bind Human IL-21 R & IL-2 R gamma Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. ILA-H52W9) with a linear range of 5-78 ng/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

51.5 kDa (IL-21 R) & 53.6 kDa (IL-2 R gamma)

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

Q9HBE5-1 (IL-21 R) & P31785-1 (IL-2 R gamma)

Preservative

Trehalose

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Cytokeratin 7 (KRT7/903), CF568 conjugate, 0.1mg/mL
BNC680903-100 1x 100 µL

Cytokeratin 7 (KRT7/903), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Phospho-Caspase-3 Antibody (pS12)
F48684-0.4ML 0.4 mL

Phospho-Caspase-3 Antibody (pS12)

Sign In for Pricing
View Details
Anti-Lyn Antibody Picoband® (FITC Conjugate)
A01424-2-FITC 100 µg/Vial

Anti-Lyn Antibody Picoband® (FITC Conjugate)

Sign In for Pricing
View Details
Anti-SNAI3 Antibody Picoband®
PB9440 100 µg/Vial

Anti-SNAI3 Antibody Picoband®

Sign In for Pricing
View Details