Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human KIR3DL3 / CD158z Protein, Fc Tag

The inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with 120 distinct polymorphic alleles of the coding sequence [

Product Specifications

Background

The inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with 120 distinct polymorphic alleles of the coding sequence [

Specifications

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 58.7 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

Q8N743-1

Expression Region

Gln 26 - Leu 322

Host

HEK293

Target

KIR3DL3

Conjugation

Unconjugated

Tag

C-Fc

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5

Additives

Trehalose

Molecular Weight

58.7 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

Q8N743-1

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Serpina3f AAV Vector (Mouse) (CMV)
43452105 1 µg

Serpina3f AAV Vector (Mouse) (CMV)

Ask
View Details
FECH (NM_001012515) Human Tagged ORF Clone
RG215223 10 µg

FECH (NM_001012515) Human Tagged ORF Clone

Ask
View Details
PE/TR Anti-Mouse TER-119 Antibody
JOT23086F 25μg

PE/TR Anti-Mouse TER-119 Antibody

Ask
View Details
CYP1B1 discontinued
312600 100 µL

CYP1B1 discontinued

Ask
View Details
Phospho-p53 (S392) Rabbit pAb
MBS8542302-01 0.1 mL

Phospho-p53 (S392) Rabbit pAb

Ask
View Details
Phospho-p53 (S392) Rabbit pAb
MBS8542302-02 0.1 mL (AF405L)

Phospho-p53 (S392) Rabbit pAb

Ask
View Details