Human B7-H4 Protein, Fc Tag, low endotoxin
V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs) . VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.
Product Specifications
Background
Specifications
Accession Number
Q7Z7D3-1
Expression Region
Phe 29 - Ala 258
Host
HEK293
Target
B7-H4
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
Endotoxin
0.01 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
51.8 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Host or Source
HEK293
Species
Human
Protein ID
Q7Z7D3-1
Preservative
Trehalose
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