Human 4-1BB Ligand / TNFSF9 (71-254) Protein, His, Flag Tag, active trimer (MALS verified)
Human 4-1BB Ligand (71-254) Protein, His, Flag Tag (41L-H52D4) is expressed from human 293 cells (HEK293) . It contains AA Arg 71 - Glu 254 (Accession # P41273-1) .
Product Specifications
Background
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD) . Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Specifications
This protein carries a polyhistidine tag at the N-terminus, followed by a flag tag. The protein has a calculated MW of 62.8 kDa. The protein migrates as 55-60 kDa under non-reducing (NR) condition (SDS-PAGE) .
Accession Number
P41273-1
Expression Region
Arg 71 - Glu 254
Host
HEK293
Target
4-1BB Ligand
Conjugation
Unconjugated
Tag
N-6xHis & N-Flag
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Human 4-1BB Ligand (71-254) Protein, His,Flag Tag (Cat. No. 41L-H52D4) at 2 μg/mL (100 μL/well) can bind Human 4-1BB, Fc Tag (Cat. No. 41B-H5258) with a linear range of 0.2-3 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
62.8 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/41L-H52D4.pdf
Species
Human
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