Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI & MALS verified)
Selected Variant
FCN-H52W7-50ug
Size: 50 µg
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Product Specifications
Background
Specifications
Accession Number
P55899-1 (FCGRT) & P61769-1 (B2M)
Expression Region
Ala 24 - Ser 297 (FCGRT) & Ile 21 - Met 119 (B2M)
Host
HEK293
Target
FcRn (FCGRT & B2M)
Conjugation
Unconjugated
Tag
C-10xHis | Native
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
32.3 kDa (FCGRT) & 11.7 kDa (B2M)
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
50ug*1
Host or Source
HEK293
Species
Human
Protein ID
P55899-1 (FCGRT) & P61769-1 (B2M)
Preservative
Trehalose
Price
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