Biotinylated Feline FcRn / FCGRT&B2M Heterodimer Protein, His, Avitag™ (MALS & SPR verified)
Selected Variant
FCN-F82W3-25ug
Size: 25 µg
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Product Specifications
Background
Specifications
Accession Number
W5VRL5-1 (FCGRT) & Q5MGS7-1 (B2M)
Expression Region
Ala 24 - Ser 297 (FCGRT) & Val 21 - Met 118 (B2M)
Host
HEK293
Target
FcRn (FCGRT & B2M)
Conjugation
Biotin-labeled
Tag
C-10xHis & C-Avi | Native
Source
Feline
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
34.0 kDa (FCGRT) & 11.5 kDa (B2M)
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
25ug*1
Host or Source
HEK293
Species
Feline
Protein ID
W5VRL5-1 (FCGRT) & Q5MGS7-1 (B2M)
Preservative
Trehalose
Price
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