Mouse FcRn / FCGRT&B2M Heterodimer Protein, His Tag (MALS & BLI verified)
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Product Specifications
Background
Specifications
Accession Number
Q61559-1 (FCGRT) & P01887-1 (B2M)
Expression Region
Ser 22 - Ser 297 (FCGRT) & Ile 21 - Met 119 (B2M)
Host
HEK293
Target
FcRn (FCGRT & B2M)
Conjugation
Unconjugated
Tag
C-10xHis | Native
Source
Mouse
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
32.9 kDa (FCGRT) & 11.6 kDa (B2M)
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
50ug*1
Host or Source
HEK293
Species
Mouse
Protein ID
Q61559-1 (FCGRT) & P01887-1 (B2M)
Preservative
Trehalose
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