Human ASGR1 / ASGPR1 Protein, Fc Tag (MALS verified)
Human ASGR1, Fc Tag (AS1-H5253) is expressed from human 293 cells (HEK293) . It contains AA Gln 62 - Leu 291 (Accession # P07306-1) .
Product Specifications
Background
ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2) . ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.
Specifications
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 52.8 kDa. The protein migrates as 65-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P07306-1
Expression Region
Gln 62 - Leu 291
Host
HEK293
Target
ASGR1
Conjugation
Unconjugated
Tag
N-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
52.8 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/AS1-H5253.pdf
Species
Human
Curated Selection
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