Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human CD3 epsilon&CD3 gamma Heterodimer Protein, Fc Tag&Fc Tag (MALS verified)

Selected Variant

CDG-H5253-100ug

Size: 100 µg

T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Product Specifications

Background

T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Specifications

Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 38.3 kDa (CD3E) and 36.9 kDa (CD3G) . Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus and subunit CD3G is fused with a human IgG1 Fc tag at the C-terminus. As a result of glycosylation, the protein migrates as 43-55 kDa under reducing (R) condition, and 90-110 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) .

Accession Number

NP_000724.1 (CD3E) & AAI13831 (CD3G)

Expression Region

Asp 23 - Asp 126 (CD3E) & Gln 23 - Ser 116 (CD3G)

Host

HEK293

Target

CD3E & CD3G

Conjugation

Unconjugated

Tag

C-Fc | C-Fc

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Human CD3E&CD3G Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. CDG-H5253) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3), premium grade (Cat. No. CDE-M120a) with a linear range of 0.8-3 ng/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

38.3 kDa (CD3E) & 36.9 (CD3G)

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

NP_000724.1 (CD3E) & AAI13831 (CD3G)

Preservative

Trehalose

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Cytokeratin 7/17 (C-46), CF488A conjugate, 0.1mg/mL
BNC880949-100 1x 100 µL

Cytokeratin 7/17 (C-46), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Cytokeratin 18 (KRT18/834), CF405S conjugate, 0.1mg/mL
BNC040834-500 1x 500 µL

Cytokeratin 18 (KRT18/834), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Anti-HE4/Wfdc2 Antibody Picoband® (HRP Conjugate)
A02685-3-HRP 100 µg/Vial

Anti-HE4/Wfdc2 Antibody Picoband® (HRP Conjugate)

Sign In for Pricing
View Details
Anti-Tubulin gamma Rabbit Monoclonal Antibody
M06313 100 µL/Vial

Anti-Tubulin gamma Rabbit Monoclonal Antibody

Sign In for Pricing
View Details
Human MMP-7/Matrilysin ELISA Kit PicoKine®
EK0463 96 Well With Removable Strips

Human MMP-7/Matrilysin ELISA Kit PicoKine®

Sign In for Pricing
View Details