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Rabbit TROP-2 / TACSTD2 Protein, His Tag (MALS verified)

Rabbit TROP-2, His Tag (TR2-R52H9) is expressed from human 293 cells (HEK293) . It contains AA Gln 35 - Pro 279 (Accession # G1T6B6-1) .

Product Specifications

Background

TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.5 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

G1T6B6-1

Expression Region

Gln 35 - Pro 279

Host

HEK293

Target

TROP-2

Conjugation

Unconjugated

Tag

C-10xHis

Source

Rabbit

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

29.5 kDa

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/TR2-R52H9.pdf

Species

Rabbit

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